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Tue 27 Feb 2018 Clinical Research

Title: Study on anal human papillomavirus infection and anal intraepithelial neoplasia among men who have sex with men in Indonesia, Malaysia and Thailand Status: Analysis

What is ANSAP?
ANSAP is a study to determine the prevalence and incidence of anal HPV infection and high-grade anal intraepithelial neoplasia (HGAIN), and evaluate their risk factors, among HIV-positive and HIV- negative men who have sex with men (MSM) in Indonesia, Malaysia and Thailand.

Who participated in ANSAP?
ANSAP enrolled 75 HIV-positive and 75 HIV-negative MSM in Kuala Lumpur, Jakarta and Bangkok. The study also enrolled 185 HIV-positive and 95 HIV-negative MSM who previously participated in the MSM VCT study. The participants were MSM ages 18 and older who had history of anal sex with men. Newly enrolled participants were enrolled for 12 months, with 3 follow-up visits. Those previously enrolled in the MSM VCT study had one follow-up visit.

Why was ANSAP important?
Men who have sex with men (MSM) are at increased risk of anal cancer. In particular, HIV-positive MSM have a higher risk of anal cancer and high-grade anal intraepithelial neoplasia (HGAIN) than HIV-negative MSM. Unfortunately, the data on anal HPV infection and HGAIN among MSM are still very limited in the region. We hope the study would support the development of HGAIN screening and treatment guidelines for the region.

*The study is sponsored by Verein AIDS Life through amfAR TREAT Asia.